They then conducted antibody tests 37 days on average after their second dose. The researchers also had participants complete a questionnaire about their vaccine-induced side effects after each dose, measuring 12 symptoms' duration and severity on a scale of 0 (not at all) to 4 (a lot). Participants were all healthy, not immunocompromised, and did not test positive for COVID-19 at the time they were enrolled. To conduct their study, the research team tested 206 employees from Walter Reed National Military Medical Center for antibodies against the coronavirus before and after they got the Pfizer vaccine. RELATED: The CDC Says 1 in 10 People Who Got Pfizer or Moderna Made This Mistake. "An antibody titer blood test is done to determine the presence (qualitative) and amount (quantitative) of antibodies in the blood." Antibodies are " specialized proteins produced by the immune system to identify and destroy foreign invaders, such as bacteria and viruses," Sanchari Sinha Dutta, PhD, explained for News Medical. Your immune response to a virus, or vaccine, is measured a variety of ways, but one of the most common is the production of antibodies. And now, a new study from the Infectious Disease Clinical Research Program (IDCRP) is shedding some light on what that might mean, specifically when it comes to side effects and the Pfizer vaccine. Over the course of the last seven months, experts have tried to send the message that while side effects are a sign your vaccine is working, no side effects aren't a sign that it isn't. But because that wasn't widely known, when people started leaving their vaccination centers feeling fine, they started to worry whether or not the vaccine was working. A little over 50 percent didn't experience any side effects at all," Thaddeus Stappenbeck, MD, Chairman of the Department of Inflammation and Immunity at Cleveland Clinic's Lerner Research Institute, explained on the hospital's website. "When you actually look at the statistics from the trials, most people didn't have side effects. And while it was reassuring to know that a fever, fatigue, and other mild to moderate reactions weren't cause for concern, what many of us didn't realize was that a lack of vaccine side effects was also not reason to sound an alarm. Doctors and public health experts spent a lot of time in the early days of the COVID vaccine rollout warning that side effects were to be expected.
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